When I drill down on that term, you can see why with posts like: Hollis-Eden Pharmaceuticals Lops A Third Of Company THQ Lays Off 100 Employees, Closes San Diego Office Citrix Cuts 10 Percent; Santa Barbara Hit And it's also interesting to see what geographies are being associated with "Layoffs" more often than others: Layoffs Woodland Hills Layoffs San Diego Layoffs Santa Monica Layoffs Los Angeles I guess this is a sign of the times. The Scott Sanfilippo Interview Media Optimization Firms Are Red Hot In Southern California in 2009

Thursday, November 19, 2009 -- San Diego �� The Great, Good, Bad and the Ugly. James Adams will moderate our distinguished panel of San Diego technology leaders and put them on the spot to label San Diego "great, good, bad, or ugly" on more than 20 factors. Panelists will Include: Ted Alexander, Managing Partner, Mission Ventures; Russ Mann, CEO and Cofounder of Covario; Allen Drennan, Founder, WireRed; and Peter Dresslar, CEO, Torrey Path. SDSIC Entrepreneur's Forum. Panelists will be asked to defend their answers and we'll let the sparks

What's going on in venture capital in San Diego? And how will the changing venture economy affect angel investors? Mission Ventures' Dave Ryan talks with Frank Peters, and offers advice for angel investors. Tags: ventures interview podcast venture peters capital ryan show mission insights dave fran For our insights and opinions section today, we're featuring a recent podcast by Frank Peters, of the Frank Peters Show , and an angel investor. What's Listen

So here's the Hot List for 1/1/2009 - 1/15/2009 Top 5 Posts The 7 Ways to Get Traffic on the Web Why You Need To Lead A Tribe - Seth Godin LA Gets Dugg, Hammered, Screwed How To Get The World Excited About Your Business –The James Siminoff Interview Viral analytics and metrics - go viral young startup Top 20 Keywords SEO Metrics Marketing Social Media Alelo Google Yahoo Mahalo MySpace Tech Coast Angels Idealab Mission Ventures Clearstone Hollywood Santa Barbara Venice San Diego Santa Monica Twiistup

San Diego-based Transaction Wireless announced this morning that it has raised $2.25M in a Series A funding. The funding came from Mission Ventures and Okapi Ventures. Leo Spiegel of Mission Ventures and Marc Averitt of Okapi Ventures have joined the firm's board as part of the funding. According to the firm, it is developing mobile infrastructure for relationship marketing, including mobile POS and mobile gift cards. Transaction Wireless said the funding will go towards sales and marketing expansion, technology development, and customer deployment.

San Diego-based VMIX , a provider of software for managing online video, said this morning that the firm has signed on automotive brand Scion. VMIX is venture backed by JK&B Capital and ATA Ventures, Mission Ventures and Enterprise Partners. Financial impact of the win was not disclosed. VMIX said that Scion will launch a new web site, www.ScionAV.com , using the firm's media management and delivery tools.

San Diego-based Nirvanix , a provider of Internet-based storage services, has raised $5M out of a $6M venture capital funding round, according to a regulatory filing. Nirvanix is venture backed by European Founders Fund, Intel Capital, Mission Ventures, Valhalla Partners, and Windward Ventures. Tags: nirvanix storage venture capita The filing, which was filed Friday, said that the funding came April 3rd. Details of the funding were not disclosed.

San Diego-based Slacker , which operates an Internet radio service, along with selling a music player linked to it service, has reportedly scored a $5M bridge financing round, according to industry publication VentureWire. Slacker is venture backed by Austin Ventures, Centennial Ventures, Mission Ventures, and Sevin Rosen Funds, and had previously raised $53.5M VentureWire cited a regulatory filing in reporting the news. in funding.

San Diego-based cloud storage provider Nirvanix has added a new customer of the firm's storage service, Nasuni , a Massachusetts startup providing virtual file server software. Nirvanix is backed by Intel Capital, Valhalla Partners, Mission Ventures, Windward Ventures, and the European Founders Fund. Nasuni said it is using Nirvanix to provide its customers with unlimited cloud capacity. Nirvanix is a provider of a cloud storage service targeted at enterprises and web application developers; Nasuni develops a virtual network attached storage (NAS) file server

San Diego-based personalized Internet radio service Slacker announced yesterday that it has linked with The Source Magazine, to launch an online, Hip-Hop radio station. Slacker is venture backed by Austin Ventures, Centennial Ventures, Mission Ventures, Rho Ventures, and Sevin Rosen Funds. Slacker said it would power The Source Digital Radio, a hip-hop station linked with The Source's print magazine and online web site. Financial details of the deal were not disclosed.